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Caris Life Sciences generation sequencing ngs
Generation Sequencing Ngs, supplied by Caris Life Sciences, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/generation+sequencing/generation+next+sequencing/pmc13272986-31-6-15
Average 86 stars, based on 1 article reviews
generation sequencing ngs - by Bioz Stars, 2026-09
86/100 stars

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Related Articles

Next-Generation Sequencing:

Article Title: Corded and hyalinized endometrioid carcinoma: A case report
Article Snippet: .. Next-Generation Sequencing performed via Caris Life Sciences revealed pathogenic mutations in ARID1A , CTNNB1 (exon 3) , PIK3R1 , PTEN , CTCF , FBXW7 , and FGFR2 with low tumor mutational burden and wildtype POLE status. ..

Article Title: Mutational analysis of microsatellite-stable gastrointestinal cancer with high tumour mutational burden: a retrospective cohort study
Article Snippet: .. Methods Molecular alterations of 48 606 gastrointestinal tumours from Caris Life Sciences (CARIS) identified with next-generation sequencing were compared among MSS–TMB-H, dMMR/MSI-H, and MSS–TMB-low (L) tumours, using χ2 or Fisher’s exact tests. ..


Article Title: Interplay between B cell and GABA metabolism (GABAm) and association with immune evasion in breast carcinoma (BC).
Article Snippet: Frances Elaine Chow, Irene Kang, Jun Yin, Alex Farrell, Vahan Martirosian, Priya Jayachandran, Evanthia T. Roussos Torres, Janice M. Lu, Heinz-Josef Lenz, Cynthia X. Ma, Heather L. McArthur, Reva K Basho, David Spetzler, Josh Neman; Department of Neurosurgery, University of Southern California, Norris Cancer Center, Los Angeles, CA; Division of Oncology, USC Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles, CA; Caris Life Sciences, Phoenix, AZ; CARIS Life Sciences, Irving, TX; University of Southern California, Los Angeles, CA; USC Keck School of Medicine, Los Angeles, CA; University of Southern California, Keck School of Medicine, Department of Oncology, Los Angeles, CA; Stony Brook Cancer Center, S. Setauket, NY; Division of Medical Oncology, Keck School of Medicine, University of Southern California, Los Angeles, CA; Washington University School of Medicine, St. Louis, MO; University of Texas Southwestern Medical Center, Dallas, TX; Cedars-Sinai Medical Center, Houston, TX


Article Title: Targeting the COP9 signalosome overcomes platinum resistance in ovarian cancer through two distinct genome stability mechanisms
Article Snippet: .. Caris Life Sciences patient samples: 12,052 high grade serous ovarian carcinoma samples were analyzed by comprehensive molecular profiling, including next-generation sequencing and whole transcriptome sequencing, performed in a CLIA/CAP/ISO15189 certified clinical laboratory (Caris Life Sciences, Phoenix, AZ, USA). ..

Article Title: 1498 Identification of Previously Unreported, Potentially Targetable Fusions in High-Grade Glioma
Article Snippet: s / Lab Invest 105 (2025) craniopharyngioma, we performed BAP1 immunohistochemistry in our malignant craniopharyngioma case, which demonstrated complete loss of nuclear expression in the tumor, suggesting a potential BAP1 mutation.. BAP1 immunohistochemistry was further performed in 10 most recent cases of benign craniopharyngiomas, all of which demonstrated normal retained nuclear expression.. Conclusions: Our literature review demonstrated that malignant craniopharyngioma tends to occur in young adults with a median overall survival of only 6 months.

Article Title: Coexisting Biopsy-Diagnosed Dementia and Glioblastoma.
Article Snippet: Chromosomal microarray was performed using the Oncoscan platform (Applied Biosystems (Affymetrix), Waltham, MA, USA). .. It is key to point out that this was a molecular diagnosis of GBM based on CNS WHO 2021 criteria given IDH-wildtype and TERT promoter mutation despite the lack of contrast enhancement on his MRI; additional whole exome next-generation sequencing via Caris Life Sciences also revealed a likely pathogenic PIK3CA mutation (c.1034A>T). ..

Sequencing:

Article Title: Interplay between B cell and GABA metabolism (GABAm) and association with immune evasion in breast carcinoma (BC).
Article Snippet: Frances Elaine Chow, Irene Kang, Jun Yin, Alex Farrell, Vahan Martirosian, Priya Jayachandran, Evanthia T. Roussos Torres, Janice M. Lu, Heinz-Josef Lenz, Cynthia X. Ma, Heather L. McArthur, Reva K Basho, David Spetzler, Josh Neman; Department of Neurosurgery, University of Southern California, Norris Cancer Center, Los Angeles, CA; Division of Oncology, USC Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles, CA; Caris Life Sciences, Phoenix, AZ; CARIS Life Sciences, Irving, TX; University of Southern California, Los Angeles, CA; USC Keck School of Medicine, Los Angeles, CA; University of Southern California, Keck School of Medicine, Department of Oncology, Los Angeles, CA; Stony Brook Cancer Center, S. Setauket, NY; Division of Medical Oncology, Keck School of Medicine, University of Southern California, Los Angeles, CA; Washington University School of Medicine, St. Louis, MO; University of Texas Southwestern Medical Center, Dallas, TX; Cedars-Sinai Medical Center, Houston, TX

Article Title: Targeting the COP9 signalosome overcomes platinum resistance in ovarian cancer through two distinct genome stability mechanisms
Article Snippet: .. Caris Life Sciences patient samples: 12,052 high grade serous ovarian carcinoma samples were analyzed by comprehensive molecular profiling, including next-generation sequencing and whole transcriptome sequencing, performed in a CLIA/CAP/ISO15189 certified clinical laboratory (Caris Life Sciences, Phoenix, AZ, USA). ..

Biomarker Discovery:

Article Title: Coexisting Biopsy-Diagnosed Dementia and Glioblastoma.
Article Snippet: Chromosomal microarray was performed using the Oncoscan platform (Applied Biosystems (Affymetrix), Waltham, MA, USA). .. It is key to point out that this was a molecular diagnosis of GBM based on CNS WHO 2021 criteria given IDH-wildtype and TERT promoter mutation despite the lack of contrast enhancement on his MRI; additional whole exome next-generation sequencing via Caris Life Sciences also revealed a likely pathogenic PIK3CA mutation (c.1034A>T). ..

Mutagenesis:

Article Title: Coexisting Biopsy-Diagnosed Dementia and Glioblastoma.
Article Snippet: Chromosomal microarray was performed using the Oncoscan platform (Applied Biosystems (Affymetrix), Waltham, MA, USA). .. It is key to point out that this was a molecular diagnosis of GBM based on CNS WHO 2021 criteria given IDH-wildtype and TERT promoter mutation despite the lack of contrast enhancement on his MRI; additional whole exome next-generation sequencing via Caris Life Sciences also revealed a likely pathogenic PIK3CA mutation (c.1034A>T). ..

Magnetic Resonance Imaging:

Article Title: Coexisting Biopsy-Diagnosed Dementia and Glioblastoma.
Article Snippet: Chromosomal microarray was performed using the Oncoscan platform (Applied Biosystems (Affymetrix), Waltham, MA, USA). .. It is key to point out that this was a molecular diagnosis of GBM based on CNS WHO 2021 criteria given IDH-wildtype and TERT promoter mutation despite the lack of contrast enhancement on his MRI; additional whole exome next-generation sequencing via Caris Life Sciences also revealed a likely pathogenic PIK3CA mutation (c.1034A>T). ..



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<t>Single-cell</t> <t>long-read</t> <t>sequencing</t> (scLRS) enhances tumor cell resolution by integrating methods for detecting splicing alterations and genetic variants. Schematic representation of how scLRS can visualize and combine multiple information types within the same cells to improve tumor cell resolution. Created in BioRender. Byrne, A. (2026) https://BioRender.com/mrmobm6 .
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Single-cell long-read sequencing (scLRS) enhances tumor cell resolution by integrating methods for detecting splicing alterations and genetic variants. Schematic representation of how scLRS can visualize and combine multiple information types within the same cells to improve tumor cell resolution. Created in BioRender. Byrne, A. (2026) https://BioRender.com/mrmobm6 .

Journal: Frontiers in Oncology

Article Title: Beyond counting: how single-cell long-read sequencing turns transcriptome complexity into precision targets

doi: 10.3389/fonc.2026.1800370

Figure Lengend Snippet: Single-cell long-read sequencing (scLRS) enhances tumor cell resolution by integrating methods for detecting splicing alterations and genetic variants. Schematic representation of how scLRS can visualize and combine multiple information types within the same cells to improve tumor cell resolution. Created in BioRender. Byrne, A. (2026) https://BioRender.com/mrmobm6 .

Article Snippet: Adopting third-generation long-read sequencing platforms, such as those developed by Pacific Biosciences (PacBio) and Oxford Nanopore Technologies (ONT), offers a solution to overcome this limitation and deepen our understanding of the transcriptome.

Techniques: Single Cell, Sequencing